The Science Behind GLP-1 Medications for Weight Loss
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Dr. James Mitchell
December 13, 2025
GLP-1 receptor agonists have revolutionized the approach to medical weight loss. Originally developed for type 2 diabetes, these medications have shown remarkable efficacy in helping patients achieve significant and sustainable weight loss.
How GLP-1 Medications Work
GLP-1 (glucagon-like peptide-1) is a hormone naturally produced in the gut. GLP-1 medications mimic this hormone, working in several ways to promote weight loss: they slow gastric emptying, reduce appetite, and help regulate blood sugar levels.
Clinical trials have shown that patients using these medications can achieve 15-20% body weight loss when combined with lifestyle modifications.
What to Expect
Weight loss with GLP-1 medications is typically gradual and steady. Most patients begin to see results within the first few weeks, with continued progress over 12-18 months of treatment.
Side effects are generally mild and often improve over time. Your healthcare provider will start with a low dose and gradually increase it to minimize any discomfort.
About Dr. James Mitchell
Medical Director
Dr. Mitchell is a board-certified physician with over 15 years of experience in men's health and hormone therapy. He leads Lvae's medical team and is passionate about making quality healthcare accessible to all.
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